Tumor Size and Axillary Lymph Node Involvement in Patients with Breast Cancer
نویسندگان
چکیده
Breast cancer is the most frequently diagnosed cancer among women and the leading cause of cancer death in females worldwide. It accounts for 30% of all female cancers and 15% of all cancer related death among women (Artaman, 2010; Garcia et al., 2011; Jemal et al., 2011). In Iran the incidence of the disease is rising, patients present with advanced stage of disease and they are younger than western population (about 10 years) than their western counterparts (ASR=25.06) (Harirchi et al., 2000; Mousavi et al., 2007). Because of high incidence rate of breast cancer among women, it is essential to identify effective strategies to manage this disease in populations. This is particularly depended on screening programs and early detection of cancer, information about risk factors, incidence of cancer in a population and the relationship
منابع مشابه
Factors Affecting axillary lymph node involvement in patients with breast cancer
Background: Breast cancer is the most commonly diagnosed and the leading cause of cancer death among females worldwide. The rate of breast cancer incidence among Iranian women is 17% of all cancers, it has been ranked first in Iran. This study aimed to investigate the factors affecting axillary lymph node involvement in female patients with breast cancer. Methods: A cross-sectional study was c...
متن کاملبررسی فراوانی نسبی بیان بیش از حدHER-2 در بیماران مبتلا به سرطان پستان پس از عمل جراحی ماستکتومی
Introduction: HER-2 is a protein receptor of growth. Approximately 25% of breast cancers have overexpress HER-2. This study was designed to determine frequency of HER-2 overexpression in patients with breast cancer. Additionally, it intended to explore its relationship with some variables such as age, histopathologic diagnosis,tumor size, axillary lymph node involvement. Methods: This analyti...
متن کاملRelationship between Non-Technical Factors and Diagnostic Accuracy of Frozen Section in Axillary Lymph Nodes in Patients with Breast Cancer
Background and purpose: Regional lymph node involvement is one of the main prognostic factors for breast cancer. Intraoperative assessment of sentinel lymph node biopsy (SLNB) by frozen section (FS) allows necessary axillary lymph node dissection (ALND) at the same time. But, false negative results are the main problems of the FS. The aim of this study was to investigate the relationship betwee...
متن کاملبررسی رابطه بین شاخص توموری 2-Her و قدرت تهاجمی سرطان پستان(متاستاز به غدد لنفاوی زیر بغل) در بیماران ماستکتومی شده در انستیتو کانسر طی سالهای 82-1380
Breast cancer is the most common site-specific cancer and is the second cause of mortality due to cancer in women. There are different prognostic factors including: axillary nodal status and tumor size(the most important factor), ER activity, PR, tumor grade and the type of histology. Other incompletely defined risk factors are: protease, catepstin, Her-2, etc. Her-2 is subtype 2 of E...
متن کاملThe Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer
Background & Objective: Recent studies from gene profiling have revealed some genes that are overexpressed in the epithelial-mesenchymal transition (EMT) process and are responsible for its initiation and activation resulting in tumor progression and metastasis. The present study aimed to assess the role of genes involved in the EMT process and the association of these genes wi...
متن کاملبررسی رابطه پروتوانکوژن HER2 با فاکتورهای پروگنوستیک سرطان پستان
Background: Breast cancer is the most common female malignancy world wide and in Iran as well and is the second cause of death due to malignancy after lung cancer. Varieties of factors such as estrogen and progesterone receptors, and axillary lymph node involvement may influence the prognosis and therapeutic approach. However, mutation in HER2 gene may also affect the prognosis. In this study...
متن کامل